Ipamorelin/CJC-1295 (no DAC) 5MG/5MG

This vial contains two distinct synthetic peptides in a 5mg/5mg presentation.

Ipamorelin is a pentapeptide, five amino acid residues in length, belonging to the growth hormone secretagogue class. It is characterised in the literature as a selective ligand at the GHS-R1a receptor.

CJC-1295 without DAC, also catalogued as Modified GRF (1-29), is a 29-residue analogue of growth hormone releasing hormone. The "no DAC" designation indicates the absence of the drug affinity complex moiety, a lysine-linked maleimide group whose presence substantially extends circulating half-life in preclinical models. Without it, the analogue is characterised by a considerably shorter half-life.

The two are catalogued together because they act on separate receptor families within the same axis, which is the basis on which they are studied in combination in preclinical work.

Supplied as a lyophilised (freeze-dried) powder in a sealed vial under vacuum. Lyophilisation removes water by sublimation, which is what allows a peptide to remain stable at ambient temperature during transit where a solution would degrade.

Reconstitution in a laboratory setting is typically performed with bacteriostatic water, introduced slowly against the vial wall rather than directly onto the powder cake. Peptide bonds are susceptible to shear, so the vial is swirled to dissolve rather than shaken.

Lyophilised and sealed, the vial is stable at 2 to 8 degrees Celsius and tolerates ambient temperature in transit. For storage beyond several months, minus 20 degrees Celsius is standard.

Once in solution the stability window shortens considerably and refrigeration is required. Repeated freeze-thaw cycles are the most common cause of degradation in a reconstituted peptide, so solutions are generally aliquoted rather than frozen and thawed as a single volume.

Every batch is independently tested through seven rounds of analysis. Identity is confirmed by mass spectrometry and purity quantified by reverse-phase HPLC, with the resulting Certificate of Analysis published against the specific batch rather than the product line.

Testing is performed by third-party laboratories operating to ISO 17025. The COA for the batch currently shipping is linked from this page and archived at /lab-tests.